Supplemental Figure 1-A topology prediction comparison for SLC45A2

2016-11-01T10:14:44Z (GMT) by Hiruni R. Wijesena Sheila M. Schmutz
A topology prediction comparison for SLC45A2 was carried out using TMHMM (v. 2.0; http://www.cbs.dtu.dk/services/ TMHMM-2.0/). a) The topology prediction for a cream Poodle. b) The topology prediction for an albino Lhasa Apso. The boxed regions indicate the eleventh transmembrane domain of SLC45A2 where the amino acid 493 is located. Comparison of the two panels clearly shows that the eleventh transmembrane domain of the albino Lhasa Apso has an altered structure.